- Contents
-
- Front matter
- Chapter 1 Clinical assessment of the renal patient
- Chapter 2 Acute renal failure
-
- Chapter 2 Acute renal failure
- Definition and epidemiology
- Causes and classification
- Prevention
- Clinical approach to ARF
- Acute or chronic renal failure?
- Assessing ARF
- The nephritic and myeloma screen
- Assessing ARF: imaging and histology
- Pre-renal ARF
- Causes of pre-renal ARF
- Volume replacement in pre-renal ARF
- Intrinsic renal ARF
- Acute tubular necrosis (ATN)
- Pathophysiology of ATN
- Management of ARF 1: a checklist
- Management of ARF 2: dangerous hyperkalaemia
- Management of ARF 3: reducing total body K
- Management of ARF 4: pulmonary oedema
- Management of ARF 5: electrolytes and acidosis
- Management of ARF 6: other strategies
- Management of ARF 7: nutrition
- Management myths
- Renal replacement therapy in ARF
- Prescribing acute haemodialysis (HD)
- Peritoneal dialysis (PD) in ARF
- The hepato-renal syndrome (HRS)
- Management of HRS
- Rhabdomyolysis
- Management of rhabdomyolysis
- Radio-contrast nephropathy (RCN)
- Tumour lysis syndrome
- ARF in sepsis
- Managing septic shock and ARF
- Chapter 3 Chronic kidney disease
-
- Chapter 3 Chronic kidney disease
- What is chronic kidney disease (CKD)?
- Pathogenesis of CKD
- Diagnosing CKD
- Progression of CKD
- Preventing progression: blood pressure
- Preventing progression: other measures
- Managing CKD
- Complications of advanced CKD
- Uraemia
- Anaemia of CKD
- Erythropoietin
- Prescribing erythropoietin
- Iron stores and iron therapy in CKD
- Renal bone disease 1
- Renal bone disease 2: physiology
- Renal bone disease 3: clinical features
- Renal bone disease 4: treatment
- Hyperphosphataemia
- Vitamin D analogues
- Calcimimetics
- Parathyroidectomy
- Calciphylaxis
- Cardiovascular disease in CKD
- Pre-transplant work-up
- Diet and nutrition in CKD
- Malnutrition in CKD
- Endocrine problems in CKD
- Palliative treatment of advanced CKD
- Chapter 4 Renal replacement therapy
-
- Chapter 4 Renal replacement therapy
- RRT: a brief history
- Introduction
- Haemodialysis (HD)
- Dialysers and membranes
- HD prescription
- Variables in the dialysis prescription
- Vascular access
- Complications of vascular access
- Acute HD complications
- Peritoneal dialysis (PD)
- Types of PD
- PD fluids
- Prescribing PD
- Peritonitis
- Other complications
- PD adequacy
- Ultrafiltration failure
- The well PD patient
- Basic transplantation
- Compatibility
- Pre-transplant assessment
- Living donor transplantation
- Pre-transplant management
- The transplant operation
- Post-transplant management
- Principles of recipient management
- Immunosuppression
- Surgical complications
- Graft dysfunction
- Acute rejection
- Chronic allograft nephropathy (CAN)
- Post-transplant infections
- Cytomegalovirus (CMV)
- BK virus nephropathy
- Post-transplant malignancy
- Expanding the donor pool
- Kidney-pancreas transplantation
- Chapter 5 Hypertension
-
- Chapter 5 Hypertension
- Hypertension facts and figures
- What is hypertension?
- Pathogenesis
- BP measurement
- Clinical assessment
- Classification of hypertension
- Treatment thresholds
- Hypertension and CV risk
- Lifestyle measures
- Secondary hypertension
- Primary hyperaldosteronism
- Specific causes of hyperaldosteronism
- Other ‘hyperaldosteronism’ syndromes
- Other causes of secondary hypertension
- Drug management of hypertension
- Drug treatment of hypertension
- Clinical trials in hypertension
- The ASCOT study
- Diuretics
- β-blockers
- α-blockers
- Calcium channel blockers
- ACE inhibitors (ACEI)
- AII receptor blockers (ARB)
- Other antihypertensives
- Resistant hypertension
- Hypertensive urgencies and emergencies
- Assessing urgencies and emergencies
- Management of urgencies and emergencies
- Orthostatic hypotension
- Chapter 6 Diseases of the kidney
-
- Chapter 6 Diseases of the kidney
- Approaching glomerular disease
- Histology of glomerulonephritis
- Acute nephritic syndrome
- Approaching acute nephritis
- General principles of management of nephritis
- Management of glomerulonephritis
- IgA nephropathy
- Management of IgA nephropathy
- Post-infectious glomerulonephritis
- Mesangiocapillary glomerulonephritis
- Hereditary nephropathies
- Other glomerulonephritides
- The nephrotic syndrome
- Minimal change nephropathy
- Membranous nephropathy (MN)
- Focal and segmental glomerulosclerosis
- Treatment of FSGS
- Thrombotic microangiopathies
- Thrombotic thrombocytopenic purpura
- Haemolytic-uraemic syndrome
- Tubulo-interstitial diseases
- Chronic tubulo-interstitial diseases
- Analgesic nephropathy
- Renovascular disease
- Management of ARAS
- Other renovascular diseases
- Adult polycystic kidney disease (APKD)
- Complications of APKD
- Other cystic kidney diseases
- Urinary tract infections
- Reflux nephropathy
- Nephrolithiasis
- Investigating recurrent stone-formers
- Acute renal colic
- Chapter 7 The kidney in systemic disease
-
- Chapter 7 The kidney in systemic disease
- Diabetic nephropathy (DN)
- Management of diabetic nephropathy
- Management of ESRD in diabetes
- The kidney in multiple myeloma
- Managing myeloma kidney
- Renal amyloid
- Other non-amyloid dysproteinaemias
- Sickle cell nephropathy
- Vasculitis and renal disease
- ANCA-positive vasculitis
- Treatment of ANCA-positive vasculitis
- Churg–Strauss syndrome
- Classical polyarteritis nodosa
- Goodpasture's disease
- Lupus nephritis
- Management of lupus nephritis
- Antiphospholipid syndrome
- Scleroderma renal crisis
- Rheumatoid arthritis
- Sarcoidosis
- HIV and renal disease
- Hepatitis B-related renal disease
- Hepatitis C-related renal disease
- The kidney in infective endocarditis
- Renal tuberculosis
- Schistosomiasis
- Malaria
- Chapter 8 Urinary tract obstruction
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- Chapter 8 Urinary tract obstruction
- Approaching obstruction
- Imaging urinary tract obstruction
- Acute obstruction
- Chronic obstruction
- PUJ and VUJ obstruction
- Retroperitoneal fibrosis
- Investigation of a renal mass
- Renal cell carcinoma
- Urothelial tumours
- Benign prostatic hypertrophy (BPH)
- Prostate cancer
- Management of prostate cancer
- Chapter 9 Fluids and electrolytes
-
- Chapter 9 Fluids and electrolytes
- Sodium: salt and water balance
- Hyponatraemia
- Management of hyponatraemia
- Hypernatraemia
- Oedema and its treatment
- Diuretics
- Potassium
- Hypokalaemia
- Bartter's, Gitelman's, and Liddle's
- Calcium, magnesium, and phosphorus
- Hypocalcaemia
- Hypercalcaemia
- Hypomagnesemia
- Hypermagnesemia
- Hypophosphataemia
- Hyperphosphataemia
- Acid—base
- Metabolic acidosis
- Renal tubular acidosis
- Lactic acidosis
- Metabolic alkalosis
- Mixed grills: acidosis and alkalosis
- Tubular rarities
- Chapter 10 Pregnancy and the kidney
-
- Chapter 10 Pregnancy and the kidney
- Renal physiology in pregnancy
- UTI in pregnancy
- Acute renal failure in pregnancy
- Hypertension in pregnancy
- Pregnancy-induced hypertension
- Pre-eclampsia and eclampsia
- Managing pre-eclampsia/eclampsia
- Chronic hypertension in pregnancy
- Pre-existing renal disease
- Disorders of the renal tract in pregnancy
- Pregnancy on dialysis
- Renal transplantation and pregnancy
- Chapter 11 Drugs and the kidney
- End matter
- Appendix
The Oxford Handbook of Nephrology and Hypertension provides clear information and practical advice about the day-to-day management of patients with renal disease. The handbook includes practical information helpful to those working ‘at the coal face’, in addition to the more detailed knowledge that enables effective ongoing patient care.
- About the Editors
-
Simon Steddon, Consultant Nephrologist, Guy’s and St Thomas’ Hospitals, London, UK
Neil Ashman, Consultant Nephrologist, St Bartholomew’s and the Royal London Hospitals, London, UK
John Cunningham, Professor of Nephrology, Royal Free & University College Hospitals, London, UK
Alistair Chesser, Consultant Nephrologist, St Bartholomew’s and the Royal London Hospitals, London, UK
- Disclaimer
Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work.
© Oxford University Press 2006
